Collaborative research defines the FOXO1-KLHL6 axis as a novel therapeutic target to enhance T cell-mediated immune response against tumors CD8⁺ T cells are the frontline soldiers of the body against ...

Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...