Clinicians frequently rely on expert opinions, which are sometimes later disproven by randomised controlled trials (RCTs).

Neoadjuvant and adjuvant capmatinib in resectable non–small cell lung cancer with MET exon 14 skipping mutation or high MET amplification: GEOMETRY-N trial. This is an ASCO Meeting Abstract from the ...

Pleural effusion is extra fluid between the pleura around your lungs and chest wall. It can cause shortness of breath, chest pain, cough, or fever. In cases of non-small cell lung cancer (NSCLC), ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

The indications for pleural drainage are diagnostic (to collect samples for cytologic, biologic, or chemical analysis) and therapeutic (to remove large fluid collections and improve respiratory ...

Pleural effusions complicate up to 57% of bacterial pneumonias. They vary in severity, ranging from uncomplicated effusions to empyema. Some require only antibiotics and observation, while others ...

Chest tube drainage is the first step in the management of complicated pleural effusions that have turned into empyema. In cases where adequate drainage cannot be provided or deloculation is required, ...

Gathering of initial clinical data guided by the differential diagnosis can orient care by identifying patients in need of urgent evaluation and by highlighting possible etiologies. The initial ...

The role of surgery for malignant pleural mesothelioma encompasses the need for rapid diagnosis, preoperative staging and surgical resection, and also the need for a greater biological understanding ...

How does fluid build up around the lungs? There are two sheets of tissue that protect the lungs. They are called pleural membranes (or pleura). In between the pleura is the pleural space. It's normal ...

Pleural effusion, sometimes called water on the lung, is a buildup of fluid between the lungs and the chest cavity. It can result from pneumonia, heart failure, cancer, and other conditions. Pleural ...