Cinchona alkaloids have a long and storied history in chemistry. Derived from Cinchona plants, members of the molecular family include the chiral catalyst cinchonidine and quinine, an early ...

For over 350 years, quinine and other extracts from the cinchona tree (Cinchona spp.) were the only effective medicines ...

Enzymes that play a crucial role in the production of the malaria drug quinine and other important cinchona alkaloids have ...

Researchers mapped the full biosynthesis of quinine in cinchona trees, identifying key enzymes and intermediates. The ...

Newly discovered enzymes found in the cinchona tree play a crucial role in the production of the malaria drug quinine and other important alkaloids. This opens up possibilities for the ...

A new metal–organic framework (MOF), APF-80, enables the crystalline sponge method to capture and analyze nucleophilic compounds. Alkaloids, a diverse group of biologically active compounds, usually ...

Nicholas P. R. Onuska is in the Department of Chemistry and at the Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina 27695, USA. Joshua G. Pierce is in the ...

What does cannabis, coca leaf, and all coffee have in common? They all contain alkaloids, a powerful group of medicinal compounds found in plants around the world. While little is presently known ...