This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...
Human development starts from the fertilization of a fully matured oocyte. Oocyte maturation, fertilization, and early embryo development before zygotic activation is characterized by the absence of ...
Writing in Molecular Therapy Nucleic Acids, researchers hypothesized that using poly(A) tail mimetics to enhance mRNA expression from haploinsufficiency-associated genes could be a disease-modifying ...
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